What do you think about Tresiba?
How’s your experience with it
Comments (68)
Switched to it a few years ago from Lantus and never looked back! It works really well for me, but everyone’s body is different.
Love it! First time in my life where I didnt need to take any correction dosages when I was a sick with the cold. Endo admitted despite that lantus is advertised as a 24hr insulin it actually only works for 21 hrs. Which explains why I had such high bg in the mornings for those almost 20 yrs using it. Constantly having to play catch up everyday without knowing it. I have elevated bg in the morning still (feet to ground and dawn phenomenon), its just not nearly as high. Cant express enough how much I love tresiba!
Type 1 for over 30 years. I currently use Tresiba and Fiasp and have been on them for a few years. Tresiba has been a huge improvement over Lantus for me. It gives me a much wider time frame ro get my dose. If I need to get it an hour or two early or an hour or two late it has never caused issues. If my Lantus was late by even 30 minutes my sugar was already rising.
Been using it for 5-10y now, works really well!
But it seems to be out of stock most of the time now, it usually takes 1-3 weeks to be restocked I don’t know if it’s the same everywhere or just my local shop that don’t want to have stock.
Early in the pandemic there were some shortages of it, but its been clean sailing with it since in my area. You might be onto something about it being your pharmacy.
Well I know it’s expensive and they get the money back for it from the government months after only when someone buys it (it’s free for patient here). Maybe the provider changed his policy and is asking for money sooner from the pharmacy.
Switching to Tresiba today and excited :)
i used to take it, its effective and gets the job done.
Just switched from Lantus and I like it! Nice to have those extra hours of coverage. I was having highs at nice on Lantus
I switched from lantus due to constant hypers in the night. Tresiba works great now and last with no sudden spike. I do find it take 2-3 days to get working and if you miss a day you're back a square 1
I did a Tresiba trial at my Endo's recommendation after several years on Lantus. About 2 months and I didn't notice much of a difference except that I found it less predictable than Lantus, so I switched back. My Endo was surprised because she had gotten a lot of feedback that Tresiba is more predictable than Lantus, but she chalked it up to "everyone is different"
When I (T2D, age 60) was first diagnosed (10/2024), I was put on Tresiba along with Lispro. Had no issues with either one. It was fun to watch blood sugar responses on the Dexcom!
Since starting Mounjaro in 11/2024, I was able to wean off of all insulin by 2/2025.
Switched recently and seems a lot better.
I have quite a high dosage long lasting insulin which was causing lumps in my legs which was making it hard for the insulin to have effect.
Moved to this and pretty much all of the lumps in my legs have gone as this is more concentrated. Love it.
Gave me horrible anxiety idk switched back to lantus
Can you expand on this a little if you feel comfortable talking about it? I take tresiba - and have for a while - but have recently started having some anxiety. I’ve never had any anxiety or anything previously so I was looking for potential reasons and this never occurred to me.
Of course so like yourself I had no issue with anxiety but I noticed I was very uncomfortable when I started taking Tresiba
Endo advised I wait at least one week, I waited two weeks, and things never got better and the only change I made in my life was switching to Tresiba
So I’m back to using Lantus now
Tresiba is what long acting insulin should be… unlike lantus
Basically gold
Tresiba and Fiasp deadly combo.
Deadly as in the best combination ever?
There's premixed one called Ryzodeg, 70/30, a blue pen. I am on that.
Thats what I use and still alive. Only was an issue because they had same colored label for awhile. They changed to different colored ones now and no longer an issue.
I just started this combo.
It works so I'm happy.
Previously used Lantus, then Basaglar. Switched to tresiba and was much better off.
Originally i was on ozembic and changed to tresiba due to pricing going up when perfectly healthy people started using ozembic to lose weight. (lol yes im not over it still)
My A1C continues to go down using it. So it’s working for me.
I use it and like it
Posted about it recently only switched to it 3 weeks ago.
Never heard of it, much to the astonishment of the people who are supposed to tell me about it 🤣
But working really well first few days was definitely higher than normal then a few days constantly going low but think I'm balanced out now and can see the improvement on my CGM showing increase in time spent in range so all positives
I like it. Works better for me than lantus did.
So much better than Lantus. Never once have I missed those dreaded Lantus lows.
Using it since I've been diagnosed (March 27th last year) - works great. Took a while for my doctor and I to find a balanced dosage. Also changed fast-acting from NovoRapid to Fiasp and it works better for me.
Tresiba (Degludec) is ultra long acting (Around 42 hours) compared to Lantus (Glargine) which is long acting (Around 22-24 hours). So the benefit is the variation in sugar reduces especially just before the dose of Degludec when compared to just before the dose of Lantus. And you can also be more flexible with the timings of Tresiba as compared to Lantus due to the ultra long acting effect.
There is a combination of Tresiba + Fiasp (Aspart) called Ryzodeg but I don’t think it’s available in USA anymore. With this you can reduce daily injections from 4 to 3 by doing Fiasp before any 2 meals and ryzodeg before the third meal.
With this you can reduce daily injections from 4 to 3 by doing Fiasp before any 2 meals and ryzodeg before the third meal.
Well, enjoy eating the same amount of carbs every day regardless of whether you are hungry or not.
There is a reason mixed insulins are rarely used outside care homes
It depends on what you want honestly. 4 injections or 3 injections per day. If you fix the carbs for one meal and take Ryzodeg during that meal it’s fine. And even if the carbs change you can make minor adjustments like in any basal bolus regimen (Example FIASP and TRESIBA).
If you don’t prefer it that’s fine but other people might want 3 injections rather than 4 and it’s a choice they have to make. Some type 2 diabetics who get exposed to insulin later on in life want less injections and physicians do prescribe it. Some type 2 patients even prefer the twice daily insulin just cause injections are lesser. As a physician I’ve prescribed all types and I personally prefer Aspart pre meals and Degludec separately (4 injections) as it is the most flexible but I feel the patient should make the
Basal insulin is more stable with Tresiba, time below target has decreased, and the dawn phenomenon has almost disappeared. I’m very satisfied.
Tresiba is what works best for me. I've used other ones (like Levimir) before, but Tresiba is just the way to go for me.
No problem been on it for two years , it’s great that the Canadian government gives universal coverage of key diabetes medications, so my insulin is free
Switched from lantus to tresiba and couldnt be happier with how it has helped me!
I switched about 6 months ago, and I can honestly say it has been incredibly effective in controlling my overnight glucose levels. Took a while to get the right dosage, but it has worked very well for me.
No side effects to report either (except weight gain).
I use it daily and works pretty good. My HbA1c is 5.9. (I use freestyle libre 2+)
way better than lantus
That thing looks like a good smoke. Which end do you light?
Was great
I find it works really well. Half the dosage as previous.
Oh, and op-amps FTW!
Had no problems, but insurance won't pay for it anymore.
Wow. First time I’ve seen someone have this happen with Tresiba. What did you have to switch to?
Lantus. I'm finishing off the last of the tresiba.
Good luck! I hate those insurance games.
Absolutely. I've got some other problems, and it's always an uphill climb.
The cost of air medevacs turned out to be worse than I thought, for instance.
I was switched to from levemir at the beginning of 2025. I went from taking 28 units of levemir to over 80 of tresiba and I was not getting anywhere near the same result. My Endo said to increase by 2 units until you get the fasting BG to 100. I couldn't get below 130.
At my next appointment I insisted they switch me to something else. They put me on Lantus and now 38 units gets me to 100 fasting BG.
Loved it when I was on it, but insurance changed and now it's way too expensive :((((
It’s the GOAT
So good, love it
Love it! Been using it for many years and works great!
It’s great. UHC stopped covering it MID YEAR (?!) so I found a coupon and paid out of pocket for it.
I liked it in pen form, liked it a lot, but when it was finally approved for the pump, I didn’t like it. It appeared to aggravate the insertion point which in turned affected the insulin’s absorption.
Not helpful, Toujero to me is way better, better profile and more stable
But for some Triesiba might be the right option, but it isn't right for everyone.
I use Fiasp and Tresiba as others as well. It works really well,
although Novo Nordisk has stopped producing Fiasp in prefilled pen so I'm gonna have to change insulin in a couple months.
First Im hearing of it and Im all for it cause itll help save space in my fridge. Endo likes to keep me very well stocked on short acting. I have months worth back stock. Roommate likes to joke Im a drug king pin when I pull it all out to find the oldest pen in the lot to use next.
Works great for me. No complaints.
I'm allergic to it
Works great for me.
I find my activity level day-to-day to be too varied for Tresiba. It stays in the system too long for me to have stable results.
Best basal so far
I loved it when my insurance covered it. Very sensitive to it though. For comparison, I take 40u of Toujeo to get a comparable 24hrs when I was taking 22u of Tresibia
idk its not approved in australia
It’s hands down the best basal insulin on the market
I had no issues with it, but switched to OP5 about a year ago. Still have three boxes (2 due to expire at the end of Jan 2026) in my fridge.